New approaches for measurement of platelet reactivity.
نویسنده
چکیده
In a highly interesting, intricate, and novel paper in this issue of Blood, Fung and colleagues have extended their previous pioneering studies and now reveal that molecules such as ATP can promote platelet activation through the P2X1 receptor.
منابع مشابه
Flow Cytometric Measurement of CD41/CD61, CD42b Platelet Receptors and Platelet Factor 3 Activity in Lyophilized Infusible Platelet Membrane Preparation
Background: The short life time of human platelet units has led to a chronic shortage of fresh platelets in blood transfusion centers. Many approaches have been investigated experimentally to produce new hemostatically active platelet products that are capable of long term storage. Infusible platelet membrane (IPM) prepared from fresh or outdated human platelets have been developed as an altern...
متن کاملElastic modulus measurement of polymer matrix nano-composites reinforced by platelet nano-clays
Polymer-clay nano-composite materials, in which nano-meter thick layers of clay dispersed in polymer matrix, have generally higher mechanical properties than normal polymeric materials. A new three-dimensional unit cell model has been developed for modeling three constituent phases including inclusion, interphase and matrix. The total elastic modulus of nano-composite is evaluated. Numerical r...
متن کاملElastic modulus measurement of polymer matrix nano-composites reinforced by platelet nano-clays
Polymer-clay nano-composite materials, in which nano-meter thick layers of clay dispersed in polymer matrix, have generally higher mechanical properties than normal polymeric materials. A new three-dimensional unit cell model has been developed for modeling three constituent phases including inclusion, interphase and matrix. The total elastic modulus of nano-composite is evaluated. Numerical r...
متن کاملFlow Cytometric Measurement of CD41/CD61 and CD42b Platelet Receptors and Clotting Assay of Platelet Factor 3 During Long Term-Storage of Platelet Concentrates
Background: The purpose of the present in vitro study was to evaluate the effect of long term storage of conventional platelet concentrates (PCs) on major platelet receptors CD42b and CD41/CD61 by flow cytometry method and also measuring the overall platelet procoagulant activity status using platelet factor 3 (PF3) assay. Materials and Methods: Six random units of conventional platelet conce...
متن کاملMeasurement of Cue-Induced Craving in Human Methamphetamine- Dependent Subjects New Methodological Hopes for Reliable Assessment of Treatment Efficacy
Methamphetamine (MA) is a highly addictive psychostimulant drug with crucial impacts on individuals on various levels. Exposure to methamphetamine-associated cues in laboratory can elicit measureable craving and autonomic reactivity in most individuals with methamphetamine dependence and the cue reactivity can model how craving would result in continued drug seeking behaviors and relapse in rea...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Blood
دوره 119 15 شماره
صفحات -
تاریخ انتشار 2012